Vitamin B12 99% White Powder - Pure Cyanocobalamin for Supplementation
Introduction to Cyanocobalamin Science
Vitamin B12 in its cyanocobalamin form represents the most stable and widely utilized version of this essential water-soluble vitamin. Our 99% pure cyanocobalamin powder meets stringent pharmacopeial standards, offering manufacturers a bright red crystalline compound with exceptional purity and consistent biological activity. As the only vitamin containing cobalt, this complex molecule plays critical roles in neurological function, red blood cell formation, and DNA synthesis, making it indispensable for addressing global B12 deficiency and supporting comprehensive metabolic health.
Key Product Specifications
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Chemical Name: α-(5,6-Dimethylbenzimidazolyl)cyanocobamide
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Molecular Formula: C₆₃H₈₈CoN₁₄O₁₄P
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Purity: ≥99% by HPLC
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Appearance: Dark red crystalline powder
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Solubility: 1.25g/100mL in water
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Stability: 24 months when stored <25°C, protected from light
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Certifications: USP, EP, JP, FDA 21CFR184.1945 GRAS
Biological Functions & Clinical Significance
1. Hematopoietic Support
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Essential for erythrocyte maturation
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Prevents megaloblastic anemia
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Works synergistically with folate metabolism
2. Neurological Maintenance
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Myelin sheath synthesis
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Neurotransmitter production
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Cognitive function support
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Peripheral nerve protection
3. Energy Metabolism
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Methylmalonyl-CoA mutase cofactor
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Mitochondrial energy production
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Reduces fatigue and weakness
4. Specialized Applications
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Homocysteine regulation
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Methylation cycle support
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DNA synthesis and repair
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Detoxification pathways
Target Populations for Supplementation
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Vegans/Vegetarians: Absent in plant foods
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Elderly (50+ years): Impaired absorption
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Pernicious Anemia Patients: Intrinsic factor deficiency
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Gastrointestinal Disorders: Crohn's, celiac, post-surgical
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Chronic Medication Users: Metformin, PPIs, nitrous oxide
Supplement & Clinical Applications
1. Oral Supplementation
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Tablets (100-1000μg doses)
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Sublingual formulations
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Chewable and gummy formats
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Multivitamin blends
2. Injectable Preparations
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Therapeutic ampoules
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B12 deficiency treatment
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Neurological support
3. Specialized Nutrition
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Infant formulas
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Enteral/parenteral nutrition
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Sports performance products
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Geriatric formulations
Technical Advantages for Manufacturers
1. Enhanced Stability Profile
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Superior to hydroxocobalamin in dry forms
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Maintains potency in multivitamin blends
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Withstands standard processing temperatures
2. Bioavailability Optimization
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Efficient conversion to active coenzymes
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Multiple absorption pathways
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Predictable pharmacokinetics
3. Formulation Flexibility
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Direct compression compatible
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Soluble forms for liquid products
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Microencapsulation options available
Quality & Safety Assurance
Global Regulatory Status
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FDA: GRAS (21CFR184.1945)
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EU: Approved nutrient
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JP: Pharmacopeia standard
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Codex: Included in NRVs
Safety Profile
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No established UL (excess excreted)
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Non-toxic at physiological doses
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70+ years of therapeutic use
Quality Control Protocol
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Identity confirmed by UV-Vis spectroscopy
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Heavy metals <10ppm
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Cyanide content <0.02%
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Microbiological standards compliance
Usage Guidelines
Recommended Daily Intakes
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Adults: 2.4μg
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Pregnancy: 2.6μg
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Lactation: 2.8μg
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Therapeutic doses: 100-1000μg
Formulation Best Practices
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Direct Compression: With suitable excipients
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Liquid Systems: Pre-dissolution recommended
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Protection: From light and moisture
Stability Considerations
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Amber glass/opaque packaging
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Storage below 25°C (77°F)
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Avoid strong oxidizing agents
Why Choose Our Cyanocobalamin?
1. Scientific Validation
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Batch-specific HPLC certification
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Forced degradation studies
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Bioavailability data
2. Technical Support
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Stability testing protocols
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Excipient compatibility
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Regulatory documentation
3. Supply Chain Excellence
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cGMP manufacturing
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Temperature-controlled logistics
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Global distribution network
Market Trends & Innovations
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Vegan Nutrition: Plant-based delivery systems
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Healthy Aging: Cognitive protection
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Personalized Nutrition: Genetic polymorphism targeting
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Advanced Delivery: Liposomal technologies
Sustainability Features
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Responsible cobalt sourcing
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Energy-efficient production
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Reduced packaging waste
| Items | Specifications |
|---|---|
| Appearance | White or of- white powder or crystlline power,odorless |
| Solubility | Very soluble in N,N-Dimethylformamide,Soluble in methanol,Sparingly soluble inglacial acetic acid, Very slightly soluble inchloroform, Practically insoluble in water. |
| Melting Point | 152°C~156°C |
| PSA | 479.7 |
| XLogP3 | 6.57018 |
| Appearance | red crystalline powder |
| Melting Point | >300 °C |
| Boiling Point | >300 °C |
| Flash Point | 48.2°F |
| Water Solubility | Soluble |
| Storage Conditions | 2-8ºC |
| Toxicity | LD50 intravenous in mouse: 2gm/kg |
| Specific rotation | SPECIFIC OPTICAL ROTATION: -59 + or - 9 DEG @ 23 °C 656 NM (DILUTE AQ SOLN) |
| Odor | Odorless |
| Taste | Tasteless |
| PH | Commercially available cyanocobalamin for injection has a pH of 4.5-7 |



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About Beijing TDD E-commerce Co., Ltd.
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